Pharmacovigilance

How we take care of life

Anti-infectives, Supportive Therapy in Oncology, and Pain Management

We care for the lives of patients by offering safe, effective, and innovative therapies with proven benefits on conditions such as bacterial infections, fungal infections, chemotherapy-induced emesis (vomiting) and new ways to treat acute pain.

Anti-infectives: bacterial and fungal infections

The widespread use of antibiotics and the lack of new therapeutic options for bacterial and fungal infections have caused an important worldwide problem due to the infections’ high morbidity and mortality. At Stendhal, we promote effective therapeutic options to combat multi-resistant strains.

Bacterial Infections

Inpatient infections are frequently caused by gram-negative bacilli (Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii), which are increasingly more difficult to treat with conventional antibiotic therapies and require medicinal products capable of counteracting multi-drug resistance; likewise, a precise and reliable approach is required through therapies that guarantee wide-spectrum action and a formulation that ensures safety and minimum toxicity issues.

Fungal Infections

Invasive fungal infections (IFI) are an ever-growing issue in critically ill patients and are associated with an increased morbidity and mortality. The rate of IFI has increased significantly at a global level, which is a serious complication for hospitalized patients due to the major advances in contemporary medicine of the last few decades, especially for critical care patients; these advances have contributed not only to greater patient survival rates but also increased incidence of opportunistic fungal infections.

Supportive Therapy in Oncology

Nausea and vomiting caused by chemotherapy and radiation therapy can significantly affect the quality of life of cancer patients. These symptoms tend to occur in up to 30% of patients and are amongst the most common side effects. They can manifest within the first 72-96 hours following the administration of chemotherapy.

It is important to prevent nausea and vomiting with proper treatment during each chemotherapy cycle. Novel antiemetics tend to prevent acute and delayed nausea and vomiting caused by chemotherapy.

Thus, it is of utmost importance to include the most effective antiemetics in the therapeutic approach to treat chemotherapy-induced nausea.

Pain Management

Nowadays, one of the greatest therapeutic needs worldwide is pain management, due to its widespread prevalence and the impact it has on the quality of life of patients. It is known that poorly treated or badly controlled pain can become chronic and affect not only the patient’s physical wellbeing, but their work, family, and social life as well.

At Stendhal, we are aware of this fact, and so we are currently working on creating a therapeutic area specifically for acute, moderate, or severe pain, with medicinal products that contribute to the safe and effective treatment of patients. We know that one of the requirements to reach therapeutical goals in pain management is the proper selection of active ingredients and pharmaceutical forms, while maintaining manufacturing quality and reliability.

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